MYC and neoplasm: Key molecular correlates include 1) upregulation of inflammasome-associated genes such as IFN gamma, and cytokines such as CCXL9 and CXCL10; 2) modulation of checkpoint molecules; 3) upregulation of APC-associated MHCII antigen presentation genes and CLEC9A and CLEC7A 4) diminished tumor cell proliferation with associated downregulation of the c-MYC oncogene pathway.