While no prior studies have identified specific roles of PPM1L and KLHL8 in schizophrenia, our data nominate PPM1L and KLHL8 as potential regulators of MAP2 phosphorylation levels, and thus as novel targets for further exploration to reverse schizophrenia-related hyperphosphorylation of MAP2. The gene discussed is PPM1L; the disease is schizophrenia.