Hematoxylin and eosin (H&E) stained sections of lung tissues from BA.1 infected K18-hACE2 mice illustrated a series of histopathological features (Figs 2 and S2 in S1 File) previously identified in SARS-CoV-2 mouse models [78], although they appeared less severe than those seen after infection of K18-hACE2 mice with original strain isolates, consistent with previous reports [74,75]. The gene discussed is KRT18; the disease is infection.