As a result, we observed less presentation of MHC-I and OVA antigen in Map3k1-mut tumor cells compared with the Map3k1-WT group using flow cytometry (Figure 4, B and C), in line with the weaker MHC-I fluorescence intensity observed on the surface of Map3k1-mut tumor cells (Figure 4D and Supplemental Figure 5B). The gene discussed is MAP3K1; the disease is neoplasm.