PTK2 and glioblastoma: The pattern of pronounced upregulation of integrin β3 in GBM and consistent overall expression of integrin β1 and FAK in all grades of gliomas was reiterated in the Western blot analysis of primary tumor cells resected from patients with glioma at the Saarland University Hospital, indicating a fair amount of overlap between gene expression in glioma tissue and protein expression in isolated glioma cells (Supplementary Fig. S5A).