ADSL and infection: Thus, the main mechanisms of action have been considered: the toroidal pore model, whereby AMPs penetrate the membrane and interact with lipids, causing toroidal pores in the membrane; the barrel‐stave model, where the peptide penetrates the membrane and creates barrel‐shaped channels; and the carpet model, where AMPs act as surfactants leading to a structural transformation of the membrane.[205] To overcome properties that restrict the clinical application of antimicrobial peptides, it is necessary to enhance AMPs' stability, delivery to the infection site, and activity in formulation.