RNA-binding proteins (RBPs), a group of proteins capable of interacting with RNA sequences both within and outside specific RNA regions, play critical roles in modulating the destiny and functionality of RNA.6 Several studies have indicated that RBPs are abnormally expressed in OC tissues and are involved in regulating OC progression.7–9 Serine/arginine-rich splicing factor 9 (SRSF9), which is considered a new biomarker and therapeutic target in various cancers, including colorectal cancer,10 hepatocellular carcinoma,11 and cervical cancer,12 plays a vital role in tumorigenesis. The gene discussed is SRSF9; the disease is colorectal cancer.