Eight genes associated with HGI were previously associated with type 2 diabetes in the GWAS catalog—ASAH1, CPED1, CPNE4, JMY, PTPRD, TMEM132D, UBASH3A, and UNC13C. A complete GWAS trait list of HGI-associated genes can be found in Supplementary Table 8. This evidence concerns the gene CPNE4 and type 2 diabetes mellitus.