Systemic inflammatory markers such as C-reactive protein (CRP), lipopolysaccharide (LPS), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), soluble CD14 (sCD14), soluble CD163 (sCD163), and D-dimer are linked to cardiovascular and liver diseases (Figure 4). This evidence concerns the gene TNF and liver disorder.