NFKB1 and colitis: Administration of the skimmed milk containing Lacticaseibacillus paracasei CCFM1222 was shown to regulate the TLR4/MyD88/NF-κB and Nrf2 signaling pathways in colitis mice and alter the gut microbiota, which indicated that Lacticaseibacillus paracasei CCFM1222 had certain anti-inflammatory effect (Guo et al., 2024).