TARDBP and amyotrophic lateral sclerosis: Amongst the main pathogenetic hypotheses associated with ALS risk, genetic susceptibility [6], abnormal function of glutamic acid [7], abnormal accumulation of TDP‐43 protein [8], dysfunction of the redox properties of free radicals [9] and depletion of neuroprotective growth factor released by the microvascular networks [10] have been widely investigated.