NPM1 and acute myeloid leukemia: Recent studies have underscored the strong interrelationship of NPM1 and panobinostat by identifying that CRISPR-edited acute myeloid leukemia cells with NPM1 knockout are transcriptionally mimicked by panobinostat [35] and that panobinostat and the NPM1 inhibitor avrainvillamide-analog-6 had similar effects on hippocampal cells [36].