In DM, erythroblastic oncogene B (ERBB2; or HER2), IFN-gamma (IFNG), IL-18, IL-1A, IL-1B, IL-1R, MAPK8 (JNK1), nuclear factor kappa beta complex (NF-κB complex), non-POU domain containing octamer binding protein (NONO), RELA proto-oncogene NF-κB subunit (RELA), signal transducer and activator of transcription 1 (STAT1), TLR9, and TNF were also predicted to be activated. The gene discussed is IL18; the disease is dermatomyositis.