CDK1 and glioblastoma: The G2/M phase has a potential role in the growth of GBM tumors88,89 Also, the inhibition of CDK1 through knockdown experiments resulted in a noteworthy reduction in the proliferation of GBM cells, specifically in U-87MG and U-251MG cell lines indicating that CDK1 is essential for the proliferation of GBM cells90.