Given that CCP5 deficiency is linked to retinitis pigmentosa, and that we recently showed that FAM161A-associated retinitis pigmentosa RP28 is due to structural defects at the level of the CC (Mercey et al, 2022), we investigated whether this structural element was affected in deglutamylase mutants. The gene discussed is FAM161A; the disease is retinitis pigmentosa.