ASC specks also strongly correlated with the levels of CRP in HC serum samples only (R = 0.76, p = 0.017 (*)), IL-2 (R = 0.67, p = 0.033 (*) in HC serum, R = −0.26, p = 0.27 in AD serum) and IL-10 in HCs only (R = 0.79, p = 0.0065 (**) in HC serum, R = 0.3, p = 0.2 in AD serum) (See the Supplementary Fig. 7C–E). The gene discussed is IL2; the disease is Alzheimer disease.