Moreover, immunohistochemistry (IHC) findings in postmortem hippocampal sections from 13 NCs and 13 donors with pathological AD showed that among the subregions GNG5 levels were significantly increased in donors with pathological AD in the CA1, CA4, and EC regions, while they tended to increase non-significantly in CA2 and CA3 (Figs. 1H and S3A). Here, GNG5 is linked to Alzheimer disease.