Moreover, given that the dysregulation of TGF‐β1/Smad pathway is a crucial pathogenic mechanism of myocardial fibrosis,18 and that miR‐425 could modulate the TGF‐β family pathway,19, 20 it is intriguing to investigate the regulatory role of miR‐425‐5p on the TGF‐β1/Smad pathway in this process. This evidence concerns the gene TGFB1 and Myocardial fibrosis.