Consistently, the levels of ANP and BNP, two classic markers of cardiac hypertrophy and HF, were significantly elevated in the TAC + rAAV9‐con group, which were also abrogated by rAAV9‐POSTN‐miR‐425‐5p administration in the TAC + rAAV9‐miR group (Figure 2G,H). Here, NPPA is linked to cardiac hypertrophy.