p53 is a critical tumor suppressor known for its regulation of cancer cell metabolism, and it has been reported to influence protein N‐glycosylation.[47, 48, 49] Our observations corroborated this finding, showing a significant upregulation of MGAT4A in EC patients harboring TP53 mutations in the TCGA‐UCEC dataset (p < 0.001; Figure8A). This evidence concerns the gene MGAT4A and neoplasm.