PDLIM2 and hepatocellular carcinoma: Ji and colleagues219 identified a circRNA called Hsa‐circ‐0003764 (circPTPN12) from the circRNA database, discovering its role in suppressing hepatocellular carcinoma progression by interacting with the PDZ domain of PDLIM2, promoting P65 ubiquitination and the assembly of the PDLIM2/OTUD6B complex, thereby highlighting the ESRP1/circPTPN12/PDLIM2/NF‐κB axis as a potential therapeutic target.