Moreover, the overlay visualization plot revealed that keywords such as ‘tirzepatide’, ‘semaglutide 2.4 mg’, ‘HFpEF’, ‘kidney outcomes’, and ‘finerenone’ are recent keywords with a higher average publication year, indicating their prominence in the field of GLP-1 agonists in cardiovascular disease (Fig. 12). The gene discussed is GCG; the disease is cardiovascular disorder.