Induce oxidative stress response, inhibit proliferation, induce various types of cell death, produce reaction oxygen species, induce differentiation and signal transducersexert, exert anti-ATLL effects, impair STAT3 signaling, target ROS/Bim and TFRC/Fe2+ pathways, induces endoplasmic reticulum (ER) stress. This evidence concerns the gene STAT3 and adult T-cell leukemia/lymphoma.