Particularly, we identified that those aged ≥60, female, non-agricultural, with a middle school education level, who smoke and drink, with a BMI < 24 kg/m2, FBG ≥ 126.00 mg/dL, waist measurement <87.50 cm, CRP < 3 mg/L, those without dyslipidemia and non-arthritis patients, are at a particularly heightened risk for stroke. The gene discussed is CRP; the disease is Stroke.