(100) found that DHA treatment of IgA nephropathy mesangial cells significantly inhibited cell proliferation, downregulated the phosphorylation levels of mTOR/S6K1 signaling pathway, and increased the expression of autophagy-related protein LC3B, indicating that DHA has anti-inflammatory and autophagy-promoting effects in IgA nephropathy. This evidence concerns the gene RPS6KB1 and IgA glomerulonephritis.