IFNG and interstitial lung disease: In B/plasma cells in the blood of patients with SS-ILD, the enriched terms were mainly related to antigen presentation and proteasome 20S subunit beta 8 (PSMB8), a gene located in the class II region of the major histocompatibility complex and induced by IFNγ, suggesting the influence of IFNγ on various cells (Figure 6D, Supplementary Figure 7F).