Although key adipocytokines known to play a role in prostate cancer include leptin, adiponectin, visfatin, fibroblast growth factor 21 (FGF21), and bone morphogenetic proteins (BMPs) (Adesunloye, 2021), there is a paucity of prognostic studies exploring the relationship between adipocytokine-related genes and PCa. Here, LEP is linked to posterior cortical atrophy.