KRAS and colorectal carcinoma: The biofilm formation ability of ETBF, which is a widely noted characteristic of carcinogenic bacteria, consisting of structures formed by bacteria through secretion, provides protection for bacteria, enhances nutrient acquisition, and promotes inter-bacterial communication.39,40 We confirmed that KRAS G12D MUT also enhanced the biofilm formation ability of ETBF in CRC (Figure 2(e)).