MPPED2 and bacterial infectious disease: We found 396 and 183 genes increased and decreased, respectively, in Smox–/– animals infected with H. pylori compared to uninfected controls; upregulated genes included those encoding for host response to bacterial infection (Wnt11, Saa3); downregulated genes included those involved in amino acid (Slc7a15, Mme) or nucleotide (Tubal3, Cda, Mpped2) metabolism, and regulation of transcription (Tbx18, Fabp1, Fbp1) and translation (Hsd17b13, Rdh16f2).