STX11 and idiopathic pulmonary fibrosis: Offenhauser and colleagues found that GFP-STX11 was predominantly located in LAMP1-labeled late endosomes and concluded that STX11 regulates the fusion between endosome and lysosome via binding to Vti1b in macrophages.15 However, whether STX11 affects the occurrence and progression of IPF by regulating autophagy remains unknown.