• Outpatient• Change in NYHA class at 72 h and 30 days, Changes in dyspnoea VAS at 72 h and 30 days, Change in lnNT-proBNP at 72 h and 30 days, Change in pedal oedema grading scale at 72 h and 30 days, Change in weight at 72 h and 30 days, Change in lnCA-125 at 72 h and 30 days, Change in urinary sodium at 24 h, 48 h, 72 h and 30 days&• Structural or functional cardiac abnormality and/or NT-proBNP >1000 pg/mL and/or• Previous treatment with loop diuretics for HF. Here, NPPB is linked to hydrops fetalis.