Assuming that PP1 and GSK3β are also transported to the synapse by the LMTK2-KLC-kinesin-1 motor complex, LMTK2 deficiency can induce further synaptic dysfunction in neurodegenerative diseases by disrupting axonal transport of these important synaptic signalling molecules. The gene discussed is LMTK2; the disease is neurodegenerative disease.