ATAD3A and neoplasm: However, it can also induce cellular senescence in tumor cells, emerging as a potential driving force of chemotherapy resistance and tumor progression.[43, 44] Given that TBK1‐mediated ATAD3A Ser321 phosphorylation is necessary for doxorubicin‐induced cellular senescence, we investigated whether targeting ATAD3A phosphorylation could be therapeutically beneficial.