The 3-(4-hydroxyphenyl)propanoic acid inhibited the secretion of proinflammatory cytokines, including interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNF-α), from lipopolysaccharide (LPS)-stimulated Caco-2 cells (human colon adenocarcinoma cell line). Here, TNF is linked to colon adenocarcinoma.