Since CAPS promotes apoptosis in different cancer cell lines through caspase-3 activation [36,103,104], we investigated the effect of CAPS on the levels of the total and cleaved form of caspase-3 in various MM lines and found that CAPS did not promote the cleavage of caspase-3 in MM cells but this preliminary evidence needs further verification. The gene discussed is CASP3; the disease is Miyoshi myopathy.