The AUC of serum insulin from 0 to 20 min was lower in the AD-Con group than in the AD-SCF and Normal-C groups, and from 20 to 90 min, the AUC of serum insulin was highest in the AD-Con group, followed by the AD-SCF and Normal-C groups (Figure 4D). The gene discussed is INS; the disease is Alzheimer disease.