Most studies agree on the interaction of BPA with various hormonal receptors, such as estrogen receptors, androgen receptors, progesterone receptors, thyroid receptors, corticosteroid receptors, PPAR-y, TLR receptors, NLR receptors, aryl hydrocarbon receptors (AhRs), GPR30 membrane receptors, retinoid X receptors (RXRs), retinoic acid receptors (RARs), liver X receptors (LXRs), and farnesoid X receptors (FXRs), all of which promote obesity. The gene discussed is NR1H4; the disease is obesity due to melanocortin 4 receptor deficiency.