AKT1 and cancer: Zughaibi et al. [202] demonstrated that diverse flavonoids (such as quercetin, myricetin, kaempferol, isorhamnetin, genistein, halangin, and hesperidin) inhibit the PI3K/Akt/mTOR pathway in various cancers, which results in inducing apoptosis, autophagy, angiogenesis inhibition, cell cycle arrest at G2/M, reduced cell migration, and reversal of drug resistance.