When metabolic syndrome parameters at initial assessment (glucose concentration, SBP, WC, triglycerides and HDL concentrations) were taken as independent variables in a standard, forward stepwise regression model, glucose concentration was the best positive predictor (b = 0.236, p < 0.05) of apelin-12 concentrations at the annual assessment (dependent variable), while glucose concentration (b = −0.281, p < 0.05) and HDL (b = −0.284, p < 0.05) were the best negative predictors of changes in vaspin concentrations (Supplemental Table S3). Here, SERPINA12 is linked to metabolic syndrome.