So, the low ω-6 to ω-3 PUFA ratio diet highlights a specific pathway related to a low ω-6 to ω-3 PUFA ratio, which, by itself, improves insulin clearance in NAFLD patients, making it potentially useful in type 2 diabetes, obese people, and, possibly, type 1 diabetes. The gene discussed is INS; the disease is type 2 diabetes mellitus.