FMR1 and fragile X syndrome: These findings reveal a FMR1-dependent control pathway for neuron-to-glia communication in neurons [98]., A study in flies has shown that as a consequence of the FMR1 gene role in translation modulation, dFmr1 loss also modulates the global metabolome, displaying reduced carbohydrate and lipid stores, with FXS flies displaying hypersensibility to starvation stress.