These observations were validated in four other GBM-derived cell lines (U118, U251, U138 and T98G) exhibiting varying levels of Tau protein expression, as well as in highly Tau-expressing neuroblastoma cells (SK-N-SH) and human differentiated epithelial cells which do not express Tau (Caco-2) [20]. The gene discussed is MAPT; the disease is neuroblastoma.