NLRP3 and gastric cancer: A study revealed that patients with GC who carried out Roux-en-Y reconstruction for radical gastrectomy exhibited an elevated level of butyrate to suppress the function of macrophages by modulating the NLRP3 pathway and decreasing the secretion of short-chain fatty acids, suggesting that short-chain fatty acids have a significant role in the prevention of colitis after GC surgery [185].