Abusaliya, A., et al. suggested that treatment with prunetin 4′-O-glucoside at 10, 20, and 40 μM induced apoptosis in Hep3B liver cancer cells through the activation of PARP and caspase-3 and also affected mitochondrial pathways through increases in caspase-9 and Bak. This evidence concerns the gene BAK1 and liver cancer.