With the goal to eliminate leukemic populations and considering that PTL and DMAPT have anti-inflammatory and antitumor action, MNC from each primary B-ALL sample were cultured in presence or absence of 5 μM of PTL, DMAPT, or PU-H71; 48 h later, apoptosis (early and late) was assessed using flow cytometry. The gene discussed is PNLIP; the disease is acute lymphoblastic leukemia.