Moreover, inflammatory cytokines, such as IL1b, IL6, TNFa, and INF, were increased, and this relates to a previously described effect by Vilchis et al. [22], where an increase in cytokine production and hematopoietic growth factors is a result of culturing B-ALL MNC for 24 h. Here, IL1B is linked to precursor B-cell acute lymphoblastic leukemia.