Interestingly, in the TDT, NTDT, and SCD groups, these enzymes were overexpressed with respect to healthy donors, whereas in the CSA patient, GLRX5 and PRDX2 were downregulated, and GPX1 and GCLC showed no significant differences compared to healthy controls (Figure 5A). The gene discussed is GCLC; the disease is chromosome-type aberration frequency.