B10.PL mice dually transgenic (Tg) for beta-actin promoter-driven SRG3 (SRG3β-actin Tg) and a myelin basic protein (MBP)-specific T cell receptor (TCR) are partially protected against experimental autoimmune encephalomyelitis (EAE) compared with MBP TCR Tg B10.PL mice [6]. Here, MBP is linked to experimental autoimmune encephalomyelitis.