In the present study, we found that MET was associated with mTOR analyzed by the STRING method with big database, and the IL-32γ overexpression reduced the mTOR and mTOR-related proteins (p-mTOR, p-4E-BP1, p-S6 kinase) expression but increased p-ULK1 in liver cancer cell lines. The gene discussed is ULK1; the disease is liver cancer.