The chemical structure of GLB is shown in Figure 1A. In the DSS-induced colitis model, mice were divided into three groups: control C57BL/6J (CTRL), NLRP3-knockout (KO) mice fed a control diet, and GLB-administered C57BL/6J mice; to all three groups, 2% DSS was administered in drinking water for 7 days (Figure 1B). Here, NLRP3 is linked to colitis.