Previous investigations utilizing GeneChip and RT-PCR analysis have identified several key factors implicated in arteriosclerosis in mice, including Apolipoprotein L 11b (Apol11b), Cathelicidin antimicrobial peptide (Camp), Chitinase 3-like 3 (Chil3), S100 calcium-binding protein A8 (S100a8), and S100 calcium-binding protein A9 (S100a9). The gene discussed is S100A8; the disease is arteriosclerosis.