dos Santos et al. found that at least one of the targets of miR-193b-5p, an miRNA whose expression is increased in lungs from ARDS patients, is occludin and that inhibition of miR-193b-5p using oligonucleotides prevents the decreases in occludin levels seen in the lungs of mice following LPS-induced lung injury as well as in cultured human microvascular endothelial cells exposed to TNFα [27]. The gene discussed is OCLN; the disease is acute respiratory distress syndrome.